Estriol Cream (recommended for vaginal dryness)

Description
Suggested Use
Ingredients
Considerations
Regular price $52.99
Progesterone

We’re Here to Help You Thrive.

Progesterone

Everything You Need to Know

Platt PRO 5% Progesterone Cream is expertly formulated to counteract the harmful effects of excess estrogen, insulin, and adrenaline.

Made with USP micronized progesterone from Mexican wild yam and is paraben free, soy free, MSM free, EDTA free and fragrance free.

Customer Reviews

Overall rating: 4.7 / 5 from 43 reviews.

Customer photo review of Estriol 2.5mg Bio-Identical Cream

So thankful for this safe form of getting estrogen into this 73 yr old body! It has helped me so much! My Dr had put me on estradiol but I did not feel good about it after reading the brochure. A friend sent me to Dr Platt’s website and I have been using it ever since! About 6 months now! Thank you so much for this product!

Estriol 2.5mg Bio-Identical Cream

Store owner replied: Hi Crystal - We are very happy you are happy with the cream and it is making a big difference :).

Customer photo review of Estriol 2.5mg Bio-Identical Cream

I like this Estriol cream far more than the one I was using. I think the pump dose was too low. Dr. Platt’s Estriol cream is the perfect pump dose and I can feel a big difference. Highly recommend!

Estriol 2.5mg Bio-Identical Cream

Customer photo review of Estriol 2.5mg Bio-Identical Cream

I love this cream! I’m 49 years old and was feeling 49! I feel a huge difference in my energy and my libido is back in high gear. Thanks Dr. Platt for a wonderful product. It’s so easy to order too! I’m a loyal client!

Estriol 2.5mg Bio-Identical Cream

I love this stuff! I’ve been using it for at least 5 years and can’t live without it. It has cut my hot flashes down by literally 99% and if I have one it’s not the melt downs I use to have. I make suppositories out of them (mold from Amazon), and insert them three times a week. I highly recommend them.

Estriol Vaginal Cream (recommended for vaginal dryness)

Both the progesterone and Estriol saved my life. I hit menopause very quickly; the transition was horrifying. If it weren’t for Dr. Platt’s information and book I don’t know that I would have had the immediate relief. I would recommend his book and hormone therapy hands-down

Estriol Vaginal Cream (recommended for vaginal dryness)

Huge improvement! No night sweats, sleeping late ke I finally should. If I am antsy at bedtime, I finally get up, put on some Progestrone Cream, less than an hour asleep until 5:00 AM the next AM. It really does work! Noticed my skin is looking less thin every where. My face is shows every AM brushing my teeth, much neck is so much less, thin looking skin, improved in three weeks, the change started showing in two weeks, week three serious noticeable change. I have recommended both products for three years to girlfriends… They ask how, do you look so much younger and energetic than us? Gave them the secret, for three years,, just sleeping and not waking up 4 times a night is a huge change, to finally look rested.

Estriol Cream 2.5 mg (recommended for vaginal dryness)

Using this twice a week on my elderly Mom to reduce, and possibly prevent, UTI’s. No side effects and no UTI’s. She was getting them monthly before this treatment. Wish doctors knew about this instead of having to hear about it on podcasts from the very few who know. UTI’s can quickly escalate to kidneys and hospitalization. My Mom was very close to death, and I want to do everything I can to prevent her from ever getting that close again. UTI’s can be treated and prevented. This seems to be a great addition to her routine.

Estriol Cream 2.5 mg (recommended for vaginal dryness)

This estriol cream is delightfully smooth and yummy on the skin. I'm putting it on my face as an anti-aging cream and I believe it's helping. I also use progesterone and love it as well. I like the packaging and ease of use. And I'm always grateful for products without fragrance. I couldn't use it otherwise. I appreciate all the hard work that Dr. Platt has put into his products. And I highly recommend them to anyone who is looking for hormones that work.

Estriol Cream 2.5 mg (recommended for vaginal dryness)

I am not giving this one star for the product, that is great. I am giving one star for the new packaging, which is horrible. The old pump for this was a little loose sometimes, but easy to fix; however, it fit perfectly into my hand and was easy dispense. The new pump is too big to fit into my hand, my fingers are barely able to reach around it (I am a female who wears medium gloves, so average size). When I finally was able to figure out a way to hold it and press the pump, the angle of the exit hole is aimed upward, it shot up and onto the wall and the floor! I am sorry to say, that I hate this new packaging so much, that I am going to look for a new version of this product until it gets changed to something that is easy to hold and dispense again.

Estriol 2.5mg Bio-Identical Cream

This is the second bottle of progesterone and first bottle of estradiol cream. Progesterone helped me to fall to sleep, and estradiol cream moisturized my skin. Great product!

Estriol 2.5mg Bio-Identical Cream

Dr. Platt products are the best! I tell all my friends to check out the website when they bring up health issues and I know I can help by referring them to the site for solid information.

Estriol 2.5mg Bio-Identical Cream

Store owner replied: Thank you Angie for being a valued customer.

Have been using it for over a month now at least. Hot flashes are still there. I am applying it at night. Wondering if I should be doing it twice a day. It’s not flashes or killers man. I get no sleep.

Estriol 2.5mg Bio-Identical Cream

These bio identical creams have been a game changer for me. Mood, sleep, motivation! They help me feel more like me!!!😍😍

Estriol 2.5mg Bio-Identical Cream

Unbelievable products. I have been going to doctors for the last 8 years with symptoms of excess fatique. I am post menopausal. Nothing was ever found but I knew something was not right. After hearing Dr Platt on a podcast and speaking about Adrenaline Domience - I bought the progesterone and estradial cream and have not looked back. I have my energy again and life back to normal.

Estriol 2.5mg Bio-Identical Cream

I use this in conjunction with the progesterone cream. It helps me not bottom out quite so hard when I get to the part of my cycle where my hormones drop. Feeling better than I have in quite awhile.

Estriol 2.5mg Bio-Identical Cream

I have recently been using this for vaginal prolapse and itching. Wouldn’t want to be without it…ever!

Estriol 2.5mg Bio-Identical Cream

This estriol cream is helping me transition off the estradiol that I have been using for years! A game changer - Thank you Dr. Platt!

Estriol 2.5mg Bio-Identical Cream

I just happened to hear a podcast for this product and thought what the heck, I’ll try it. I just started using both the progesterone and the Estriol creams a couple of months ago. They work so well, I have stopped buying my other expensive vitamins and creams and no longer experience “heat waves.” Not only does it work so well but I’m now saving more money. Thank YOU

Estriol 2.5mg Bio-Identical Cream

So easy to use! I use it on my face then whatever is leftover I put on my wrists- feel better, look better instantly!

Estriol 2.5mg Bio-Identical Cream

I’m still using the initial one I bought. I started having warm flashes frequently but they have slowed down some. Other than this I don’t see any changes or notice them. I work 12 hour shifts over night so I am usually tired all the time. I’m hoping this product will help with the constant fatigue. I will continue to use this product because my body is depleted of these hormones. Thank you for coming up with a product that is not harmful to the body.

Estriol 2.5mg Bio-Identical Cream

It has made my hot flashes bearable. I have to use it every other night in order to cut down on the them, but if I have a hot flash it's not near as severe. Thank you Dr Platt.

Estriol 2.5mg Bio-Identical Cream (bio-identical)

Our Best-Selling

Hormone Support Solutions

Add Platt Pro 5% Progesterone Cream Fragrance Free to the cart
Add Platt Pro 5% Bio-Identical Progesterone Cream w/Lavender Essential Oil to the cart
Add Estriol Cream (recommended for vaginal dryness) to the cart

Frequently Asked Questions

What are the benefits of estriol vaginal cream?
Vaginal dryness is most often caused by declining estrogen levels, which thin and dry the vaginal tissues — leading to discomfort, irritation, and sometimes pain during intercourse. Estrogen also supports healthy pH and moisture in the vaginal canal. When it falls, the tissues lose elasticity and lubrication.
Is estriol cream safe for menopause?
Unlike systemic hormone therapies, vaginal estriol creams primarily work locally, meaning they deliver benefits where you need them without significant systemic hormone exposure.
Estriol vs Estradiol — Which Is Better?
Estriol (E3) and estradiol (E2) are both forms of estrogen, but they serve different purposes. Estradiol is the strongest estrogen and is commonly used in systemic hormone therapy to help with symptoms like hot flashes and bone loss. Estriol is a gentler estrogen often used in vaginal creams to support vaginal dryness, tissue health, and urinary comfort during menopause. For localized vaginal symptoms, many women prefer estriol because it works directly on vaginal tissues with less systemic effect.
How long does estriol cream take to work?
Most women begin to notice improvement in vaginal dryness, irritation, or discomfort within about 10-14 days of consistent daily use. Full benefits—such as improved vaginal moisture, tissue elasticity, and comfort—may take up to 4-12 weeks or up to 3 months as estrogen gradually restores the vaginal tissues. Results vary depending on hormone levels and symptom severity.