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Many people struggle with weight management despite making healthy choices during the day. One factor that is often overlooked is what happens to the body during sleep — specifically, how hormonal activity overnight may influence metabolism and body composition.
Dr. Platt’s framework suggests that when blood sugar drops during the night, the body may release adrenaline to raise glucose levels. This adrenaline surge can disrupt sleep quality and may contribute to the body storing excess glucose as fat during overnight hours.
Signs that nighttime adrenaline may be a factor include:
- Waking between 2–4 AM
- Teeth grinding or jaw tension during sleep
- Restless leg syndrome
- Difficulty staying asleep
- Feeling unrested in the morning
Supporting stable blood sugar before bed — through a small low-glycemic snack — and using bio-identical progesterone cream to support healthy hormonal balance may be helpful strategies for some individuals.
For a full discussion of this topic, see Dr. Platt’s book Adrenaline Dominance and the Adrenaline Dominance Diet Meal Plan, both available at plattwellness.com.
The information in this article is for educational purposes only and does not constitute medical advice. Please consult a qualified healthcare provider for personalized weight management guidance. These statements have not been evaluated by the Food and Drug Administration.
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
3 comments
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Kim Butler on
I’ve already been used in the progesterone cream for two months. Since I had a hysterectomy about 20 years ago, Sure I need to use the estriol as well. I feel like I’m having unexplained weight gain even though I eat a healthy diet and exercise five days a week as usual. You think the estradiol would help that? I feel bloated and crampy in my stomach a lot. I’m just trying to find an answer.
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Dr. Michael E. Platt on
I agree that you had contributing factors to your weight gain, especially the steroids for pain and being bedridden.
But I am sure that you were hormonally challenged as well. -
Jonna on
Im pretty sure my weight gain is from my early hysterectomy, no hormone monitoring, massive steroids for pain…So,much more than the law allows and this has totally put on weight!! And,Ive been bedridden for about 3 yrs!! Have gut and digestive issues,leaky gut syndrom-:
I’ve already been used in the progesterone cream for two months. Since I had a hysterectomy about 20 years ago, Sure I need to use the estriol as well. I feel like I’m having unexplained weight gain even though I eat a healthy diet and exercise five days a week as usual. You think the estradiol would help that? I feel bloated and crampy in my stomach a lot. I’m just trying to find an answer.
I agree that you had contributing factors to your weight gain, especially the steroids for pain and being bedridden.
But I am sure that you were hormonally challenged as well.
Im pretty sure my weight gain is from my early hysterectomy, no hormone monitoring, massive steroids for pain…So,much more than the law allows and this has totally put on weight!! And,Ive been bedridden for about 3 yrs!! Have gut and digestive issues,leaky gut syndrom-: