Hey Doc,Can progesterone cream be used throughout the female cycle if being used for adrenaline dominance issues? Also, does high cortisol as determined by a 4-pt saliva test indicate adrenaline dominance?Thanks, Julia __________________________________________________________________________ Dear Julia, Progesterone cream can be used throughout the female cycle in order to maximize its effect on managing adrenaline and insulin. The only exception to this in those situations when a woman is trying to get pregnant. In that case, progesterone should not be used for the first 7-10 days of the cycle to avoid the possibility that it might prevent ovulation. A high cortisol always...